| Date | Location | Result | |
| May 15, 2010 | DeLand, Fla. | Lipscomb 11, USC Upstate 0 | Box score |
| May 15, 2010 | DeLand, Fla. | USC Upstate 2, Stetson 1 | Box score |
| May 14, 2010 | DeLand, Fla. | USC Upstate 7, Jacksonville 4 | Box score |
| May 13, 2010 | DeLand, Fla. | USC Upstate 3, Lipscomb 2 | Box score |
| May 13, 2010 | DeLand, Fla. | Kennesaw State 1, USC Upstate 0 | Box score |
| May 08, 2010 | Buies Creek, N.C. | USC Upstate 1, Campbell 0 | Box score |
| May 08, 2010 | Buies Creek, N.C. | Campbell 2, USC Upstate 1 | Box score |
| May 06, 2010 | Spartanburg, S.C. | USC Upstate 9, Appalachian State 8 | Box score |
| May 06, 2010 | Spartanburg, S.C. | USC Upstate 3, Appalachian State 0 | Box score |
| Apr 25, 2010 | Spartanburg, S.C. | USC Upstate 4, East Tennessee State 2 | Box score |
| Apr 25, 2010 | Spartanburg, S.C. | USC Upstate 3, East Tennessee State 0 | Box score |
| Apr 21, 2010 | Spartanburg, S.C. | USC Upstate 3, Winthrop 1 | Box score |
| Apr 21, 2010 | Spartanburg, S.C. | USC Upstate 1, Winthrop 0 | Box score |
| Apr 17, 2010 | Spartanburg, S.C. | Mercer 5, USC Upstate 4 | Box score |
| Apr 17, 2010 | Spartanburg, S.C. | USC Upstate 2, Mercer 0 | Box score |
| Apr 16, 2010 | Spartanburg, S.C. | Kennesaw State 10, USC Upstate 2 | Box score |
| Apr 16, 2010 | Spartanburg, S.C. | USC Upstate 2, Kennesaw State 1 | Box score |
| Apr 14, 2010 | Spartanburg, S.C. | USC Upstate 5, South Carolina 0 | Box score |
| Apr 13, 2010 | Spartanburg, S.C. | USC Upstate 5, Charlotte 4 | Box score |
| Apr 13, 2010 | Spartanburg, S.C. | USC Upstate 3, Charlotte 2 | Box score |
| Apr 10, 2010 | Jacksonville, Fla. | Jacksonville 4, USC Upstate 3 | Box score |
| Apr 10, 2010 | Jacksonville, Fla. | Jacksonville 7, USC Upstate 2 | Box score |
| Apr 09, 2010 | Jacksonville, Fla. | North Florida 3, USC Upstate 2 | Box score |
| Apr 09, 2010 | Jacksonville, Fla. | USC Upstate 4, North Florida 0 | Box score |
| Apr 6, 2010 | Columbia, S.C. | USC Upstate 6, South Carolina 0 | Box score |
| Apr 03, 2010 | Spartanburg, S.C. | Stetson 1, USC Upstate 0 | Box score |
| Apr 03, 2010 | Spartanburg, S.C. | USC Upstate 7, Stetson 2 | Box score |
| Apr 02, 2010 | Spartanburg, S.C. | USC Upstate 11, Florida Gulf Coast 0 | Box score |
| Apr 02, 2010 | Spartanburg, S.C. | USC Upstate 3, Florida Gulf Coast 0 | Box score |
| Mar 30, 2010 | Boiling Springs, NC | USC Upstate 6, Gardner-Webb 0 | Box score |
| Mar 30, 2010 | Boiling Springs S.C. | USC Upstate 6, Gardner-Webb 1 | Box score |
| Mar 27, 2010 | Nashville, Tenn. | Lipscomb 6, USC Upstate 1 | Box score |
| Mar 27, 2010 | Nashville, Tenn. | Lipscomb 4, USC Upstate 0 | Box score |
| Mar 26, 2010 | Nashville, Tenn. | USC Upstate 2, Belmont 0 | Box score |
| Mar 26, 2010 | Nashville, Tenn. | USC Upstate 7, Belmont 2 | Box score |
| Mar 23, 2010 | Greenville, S.C. | USC Upstate 3, Furman 1 | Box score |
| Mar 23, 2010 | Greenville, S.C. | USC Upstate 1, Furman 0 | Box score |
| Mar 21, 2010 | Greensboro, N.C. | USC Upstate 6, North Carolina A&T 0 | Box score |
| Mar 21, 2010 | Greensboro, N.C. | USC Upstate 1, North Carolina A&T 0 | Box score |
| Mar 18, 2010 | Spartanburg, S.C. | USC Upstate 5, Charleston Southern 3 | Box score |
| Mar 18, 2010 | Spartanburg, S.C. | USC Upstate 3, Charleston Southern 1 | Box score |
| Mar 16, 2010 | Spartanburg, S.C. | Coastal Carolina 4, USC Upstate 2 | Box score |
| Mar 16, 2010 | Spartanburg, S.C. | USC Upstate 4, Coastal Carolina 0 | Box score |
| Mar 13, 2010 | Rock Hill, S.C. | USC Upstate 8, Winston-Salem St. 0 | Box score |
| Mar 13, 2010 | Rock HIll, S.C. | USC Upstate 2, Hartford 0 | Box score |
| Mar 09, 2010 | Spartanburg, S.C. | USC Upstate 9, Western Carolina 3 | Box score |
| Mar 09, 2010 | Spartanburg, S.C. | USC Upstate 2, Western Carolina 1 | Box score |
| Feb 24, 2010 | Spartanburg, S.C. | USC Upstate 3, Siena 0 | Box score |
| Feb 23, 2010 | Spartanburg, S.C. | USC Upstate 6, Tusculum 1 | Box score |
| Feb 23, 2010 | Spartanburg, S.C. | USC Upstate 8, Tusculum 0 | Box score |
| Feb 21, 2010 | Spartanburg, S.C. | UMBC 2, USC Upstate 1 | Box score |
| Feb 20, 2010 | Spartanburg, S.C. | Liberty 12, USC Upstate 2 | Box score |
| Feb 20, 2010 | Spartanburg, S.C. | USC Upstate 9, Eastern Kentucky 1 | Box score |
| Feb 19, 2010 | Spartanburg, S.C. | USC Upstate 3, UMBC 1 | Box score |
| Feb 12, 2010 | Columbia, S.C. | Coastal Carolina 6, USC Upstate 1 | Box score |
| Feb 12, 2010 | Columbia, S.C. | USC Upstate 2, Charleston Southern 1 | Box score |